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Lactoferrin is a natural zhelyazoprenasyasht glycoprotein playing an important role in nonspecific defenses. Potent broad-spectrum antibiotic, which, unlike pharmaceuticals such fights with multiple viruses (herpes simplex, hepatitis C virus, adenoviruses, cytomegalovirus), and it is also effective against bacteria, fungi and protozoa. Lactoferrin, a strong antioxidant, significantly reduced the harmful effects of free radicals. Protects the body from injury, as has the ability to modulate the inflammatory process, increasing the resistance of the organism. Occurs in two forms in the body: hololaktoferin (associated with iron) and apolaktoferin (no iron).

What we know about lactoferrin?

Lactoferrin is a multifunctional extracellular glycoprotein, acting as a key element of innate immunity in mammals. It belongs to the main serum transport proteins responsible for immune protection of mucosal surfaces of respiratory, gastrointestinal and genitourinary system, but can be found in various body fluids and secretions (tears, saliva, bronchial mucus, bile, pancreatic juice, intestinal and genital secretions), which are rich in antimicrobial peptides with anti-inflammatory action. For example, each molecule of protein lactoferrin can be connected with two Fe3 ion.

It is known that the majority of pathogenic bacteria require iron for growth and its affinity to it. Which means that their virulence is directly dependent on the availability of iron in the environment in which to develop. A healthy organism is characterized by low concentrations of elements in mucosal secretions, but in the presence of pathology of iron concentration increases, which favors the development of the bacteria. Lactoferrin as a core component of these secretions is in its apo-form. It connects through stronger links with iron and thus "deprive" him of bacteria.

The presence of extracellular space in apolaktoferin maintain low levels of iron and successfully prevent bacterial growth. Scientists prove that this lactoferrin has the ability to inhibit the development of many bacterial species.

Who is the main source of protein?

For the first time lactoferrin is isolated from milk secretion at concentrations of about 7 mg / ml, but later found that is synthesized primarily by the roof epithelial cells and is secreted in mucosal secretions at concentrations of 2 mg / ml. Richest source of colostrum is lactoferrin, which has been known that it is the first milk of mammals that mothers feed their offspring. Its production lasts 48 to 72 hours before the appearance of normal milk.

Colostrum contains a high concentration of vital growth and modulating the development and maturation of immune factors that are crucial for normal feeding and development of all tissues and organs in the body. Its formation is much more complicated than ordinary milk and its ingredients are not found in such large concentrations elsewhere in nature.

For industrial use lactoferrin derived from bovine colostrum from cows, because it is an ideal source of natural antibodies restezha factors, and other immune factors, especially nutrients. In addition, colostrum from cows is perfectly safe, wholesome and natural food that can be consumed indefinitely and there is absolutely no level of toxicity. And in recent years by methods of genetic engineering to produce "human" lactoferrin.

Main functions of lactoferrin

Antibacterial activity - due to the binding of lactoferrin with iron, on the other hand it is associated with vitamin B12, thereby making them unavailable to bacteria, which significantly limit their reproduction. Recently been demonstrated and proteolytic activity zhelyazoprenasyashtiya protein, which targets certain bacterial virulence factors and reduce pathogens. Lactoferrin is especially important for babies and people with weakened resistance. Is effective against E. coli, Salmonella, Staphylococcus, Listeria, Candida.

Antifungal and antiparasitic action - related to the absorption of lactoferrin on the cell surface of pathogenic microorganism.

Antiviral activity - protein prevents the attachment of viruses to cell walls and their penetration into cells. This means that it is a key molecule for the immune system. For example, it was found that patients infected with the AIDS virus, the levels of lactoferrin in the oral cavity are greatly reduced, making them particularly susceptible to various infections.

Inflammatory action - lactoferrin has the ability to bind to polysaccharides isolated from microorganisms, thus it activates other immune cells.

Rich content of essential oil makes very good herb potogonno and temperature decreasing means. Many herbalists even think anasonat appropriate aid for gout, headache, boils and swellings.

Probiotic effect - lactoferrin inhibits the development of harmful bacteria in the gut and supporting the development of bifidobacteria contributing to the normal microflora. He favorably influence the treatment of various allergic and infectious diseases associated with gut if taken regularly and in sufficient quantities.

Anticancer action - made sufficiently in vivo and in vitro experiments demonstrating the anticancer properties of glycoproteins. It is also a potent inhibitory activity of lactoferrin specifically on pancreatic cancer, it is an important part of rescue therapy.

Anticancer action - made sufficiently in vivo and in vitro experiments demonstrating the anticancer properties of glycoproteins. It is also a potent inhibitory activity of lactoferrin specifically on pancreatic cancer, it is an important part of rescue therapy.

Viruses constantly mutate in a toxic environment around us, and growing resistance of bacteria to antibiotics, which are no longer the "miracle cure", do lactoferrin indispensable tool in the fight against them.

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